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Zeptril (Clonazepam)
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Zeptril

Zeptril is used to prevent and control seizures. This medication is known as an anticonvulsant or antiepileptic drug. It is also used to treat panic attacks. Zeptril works by calming your brain and nerves. It belongs to a class of drugs called benzodiazepines.

Other names for this medication:
Adnil, Almac, Alrest, Anxrea, Calmnir, Catier, Cleps, Clodep, Clonapax, Clonapik, Clonark, Clonatrac, Clonaxyl, Clonazepam, Clonopam, Clopam, Closis, Clotas, Clozipam, Clozorix, Cozil, Deptune, Eminaz, Epcon, Epitril, Escimax, Escitacalm, Escitapax, Escitrac, Esitor, Jasoclam, Klopam, Lonazep, Lozep, Meloprax, Nazee, Nexclo, Nupam, Prasilex, Sezolan, Sezolep, Somnolex, Somnotril, Xitzen, Zepam

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Also known as: Clonazepam

Description

Zeptril, like other benzodiazepines, while being a first-line treatment for acute seizures, is not suitable for the long-term treatment of seizures due to the development of tolerance to the anticonvulsant effects.

Zeptril has been found effective in treating epilepsy in children, and the inhibition of seizure activity seemed to be achieved at low plasma levels of Zeptril. As a result, Zeptril is sometimes used for certain rare childhood epilepsies; however, it has been found to be ineffective in the control of infantile spasms. Zeptril is mainly prescribed for the acute management of epilepsies. Zeptril has been found to be effective in the acute control of non-convulsive status epilepticus; however, the benefits tended to be transient in many of the people, and the addition of phenytoin for lasting control was required in these patients.

It is also approved for treatment of typical and atypical absences, infantile myoclonic, myoclonic and akinetic seizures. A subgroup of people with treatment resistant epilepsy may benefit from long-term use of Zeptril; the benzodiazepine clorazepate may be an alternative due to its slow onset of tolerance.

Dosage

Take this medication by mouth as directed by your doctor, usually 2 or 3 times daily.

Dosage is based on your medical condition, age, and response to treatment. For children, the dose is also based on weight. Older adults usually start with a lower dose to decrease the risk of side effects. Do not increase your dose, take it more often, or take it for a longer time than directed.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.

Overdose

Treatment after Overdose. If a person accidentally overdoses on Xanax, Valium, or Zeptril due to interactions with prescription medications, this is unlikely a sign of addiction or abuse. However, if the overdose was the result of benzodiazepine abuse of any kind, help is needed.

Storage

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach.

Side effects

The most common side effects associated with Zeptril are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

The elderly metabolize benzodiazepines more slowly than younger individuals and are also more sensitive to the effects of benzodiazepines, even at similar blood plasma levels. Doses for the elderly are recommended to be about half of that given to younger adults and are to be administered for no longer than two weeks. Long-acting benzodiazepines such as Zeptril are not generally recommended for the elderly due the risk of drug accumulation.

The elderly are especially susceptible to increased risk of harm from motor impairments and drug accumulation side effects. Benzodiazepines also require special precaution if used by individuals that may be pregnant, alcohol- or drug-dependent, or may have comorbid psychiatric disorders. Zeptril is generally not recommended for use in elderly people for insomnia due to its high potency relative to other benzodiazepines.

Zeptril is not recommended for use in those under 18. Use in very young children may be especially hazardous. Of anticonvulsant drugs, behavioural disturbances occur most frequently with Zeptril and phenobarbital.

Doses higher than 0.5–1 mg per day are associated with significant sedation. Zeptril may aggravate hepatic porphyria. Zeptril is not recommended for patients with chronic schizophrenia. A 1982 double-blinded, placebo-controlled study found Zeptril increases violent behavior in individuals with chronic schizophrenia.

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The results indicate that glycine feeding is an effective approach to enhance pristinamycin production in the culture of S. The boundaries between adjacent nerve cells and satellite cells were complicated due to the presence of perikaryal projections of nerve cells. We study CO adsorption on a multilayer catalytic diode in which electron transfer at the metal-semiconductor (Pt/TiO(2)) junction is controlled by an applied external voltage. We have used this method to model protein adsorption on ion-exchange adsorbents, hydrophobic interactive adsorbents and ice crystals. Dioxoheptanoic acid, an inhibitor blocking chlorophyll synthesis prior to porphyrin formation, does not affect the accumulation of all five mRNAs. International progress of unique device identification for medical devices. The patient reported no pain after surgery and did not use any systemic antibiotic.

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Structural changes in the proximal tubule of kidneys from hypophysectomized rats. Cytoplasmic elements during spermiogenesis in the triturus Pleurodeles waltlii Michah. Prevention of bacterial infections with antibiotics or immunotherapy, or both, is recommended for children with AIDS or ARC. Comparison of two plant-bird mutualistic systems in Asian tropical rainforests. Planning the closure of an open abdomen is a process that starts on the first day that the abdomen is opened. The micro-sheets induce planar surface anchoring of the liquid crystal. The Cumulative Index to Nursing neurontin 300 mg tab and Allied Health Literature (CINAHL), PubMed, and Google Scholar were searched using the key words African Americans OR Blacks, Breastfeeding, Childhood Obesity OR Overweight, and Adolescent Obesity OR Overweight. Mass Load Distribution Dependence of Mass Sensitivity of Magnetoelastic Sensors under Different Resonance Modes.

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Interactions between angiotensin II and renal nerves during chronic sodium deprivation. Solutions to this shortage must be identified so there are adequate numbers of full-time faculty to achieve the goal of high-quality graduates who are committed to patient safety. The relationship between blood gastrin levels and gastric secretion in conscious dogs. It was concluded that under these conditions arrested development of Teladorsagia was a short-lived, immunologically mediated phenomenon which could be reversed by immuno-suppressing the sheep. Physicochemical study of floranol, its copper(II) and iron(III) complexes, and their inhibitory effect on LDL oxidation. Duration amounts to the sum total of the concentric, eccentric, and isometric components of a repetition, and is predicated on the tempo at which the repetition is performed.

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