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Zinacef (Cefuroxime)

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Zinacef is used for treating bacterial infections (sinus, skin, lung, urinary tract, ear, and throat). It may also be used to treat Lyme disease and gonorrhea. Zinacef is a cephalosporin antibiotic. It works by interfering with the formation of the bacteria's cell wall so that the wall ruptures, resulting in the death of the bacteria.

Other names for this medication:
Altacef, Cefakind, Ceftum, Cefuroxime, Kefurox, Oratil, Pulmocef, Stafcure, Supacef, Zefu, Zinacef, Zocef

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Also known as: Cefuroxime


Zinacef eye drops and eye ointment are used to treat bacterial eye infections. Eye infections are a common cause of conjunctivitis. In conjunctivitis, your eye becomes inflamed, feels gritty, and may water more than usual. The white of your eye may look red, and your eyelids can become swollen and stuck together with a discharge when you wake up in the morning. Only one eye may be infected to begin with, but it often spreads to both eyes.

Most cases of infective conjunctivitis clear within a few days without treatment. For more severe infections, or for infections which do not clear on their own, an antibiotic eye drop or ointment such as Zinacef can be helpful.

Zinacef works by helping to kill the bacteria which are causing the infection. It is available on prescription. You can also buy the drops and the ointment from a pharmacy, without a prescription, if it is for conjunctivitis in an adult or a child over 2 years of age. Do not use Zinacef eye drops or ointment for a child under 2 years old, unless it has been prescribed by a doctor.


Use Zinacef exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Zinacef oral is taken by mouth.

Zinacef oral may be given as a single dose to treat gonorrhea. For most other infections, Zinacef oral is usually given for 7 to 10 days, or for 20 days to treat early Lyme disease. Follow your doctor's dosing instructions very carefully.

Swallow the tablet whole and do not crush, chew, or break it. You may take the tablet with or without food.

Tell your doctor if a child taking this medicine cannot swallow a tablet whole.

Zinacef injection is injected into a muscle, or as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.

Prepare an injection only when you are ready to give it. Do not use if the medicine lhas changed colors or has particles in it. Call your pharmacist for new medicine.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Zinacef will not treat a viral infection such as the flu or a common cold.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using this medicine.

Store the oral medicine at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

The injection is a powder that must be mixed with a diluent before you inject the medicine. If the Zinacef injection is frozen when you receive it, thaw the medicine at room temperature (do not use heat).

After thawing, you may store the injection at room temperature for up to 24 hours, or in a refrigerator for up to 7 days. Do not refreeze the medicine once it has been thawed.

Detailed Zinacef dosage information


Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include seizure (black-out or convulsions).


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Zinacef are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Zinacef if you have an allergy to any type of penicillin, or if you are allergic to cefuroxime or any other cephalosporin antibiotic (cefdinir, cefalexin, Keflex, Omnicef, and others).

To make sure Zinacef is safe for you, tell your doctor if you have ever had:

a stomach or intestinal disorder such as colitis; kidney disease; liver disease; or if you are malnourished.

Tell your doctor if you are pregnant or breastfeeding.

Some antibiotics can make birth control pills less effective. Ask your doctor about using a non-oral birth control to prevent pregnancy. This includes injections, implants, skin patches, vaginal rings, condom, diaphragm, cervical cap, or contraceptive sponge.

Zinacef is not approved for use by anyone younger than 3 months old.

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